Mild hypervalent iodine mediated oxidative nitration of N-aryl sulfonamides.
نویسندگان
چکیده
An oxidative and acid-free method for the nitration of N-aryl sulfonamides has been developed using a combination of sodium nitrite as cheap and easy to handle NO2-source and the hypervalent iodine reagent PIFA as stoichiometric oxidant. Under very mild reaction conditions, the desired mononitrated aryl sulfonamides were isolated in up to 87% yield. This is the first example of an iodane-mediated oxidative nitration.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 72 شماره
صفحات -
تاریخ انتشار 2014